TILMICON-250
COMPOSITION
100 ml of preparation contains following active substance:
Tilmicosin – 25.0 g;
Additional ingredients: propylene glycol, benzyl alcohol, purified water.
PHARMACOLOGICAL PROPERTIES
Tilmicosin is a semi-synthetic antibiotic of macrolides group that in low concentration acts bacteriostatically and in high concentration has a bactericidal effect against Gram-positive and Gram-negative microorganisms like Ornithobacterium rhinotracheale, Pasteurella spp., Haemophilus spp., Actinomyces spp., Corynebacterium spp., Staphylococcus aureus, Clostridium perfringens, as well as against Mycoplasmas (Mycoplasma spp.).
The mechanism of product action is to inhibit protein synthesis in the bacterial cell by binding to 50S-ribosomal subunits.
ADMINISTRATION
Treatment of calves up to 3 months of age in case of respiratory diseases caused by Mycoplasma bovis, M.dispar, Pasteurella multocida, P.haemolytica and other microorganisms, susceptible to Tilmicosin.
Treatment of swine in case of bacterial pneumonia caused by Mycoplasma hyopneumoniae, Pasteurella multocida, Actinobacillus pleuropneumoniae and other pathogens susceptible to Tilmicosin.
Treatment of poultry (chicks, broilers, replacement chicks, parent flocks) and turkeys in case of respiratory diseases, caused by Mycoplasma gallisepticum, M.synoviae, M.meleagridis, Ornithobacterium rhinotracheale, Pasteurella multocida and other pathogens susceptible to Tilmicosin.
ROUTE OF ADMINISTRATION AND DOSAGES
ANIMAL SPECIES |
DOSAGE |
DURATION OF TREATMENT |
METHODS |
|---|---|---|---|
Calves |
1 ml of product per 20 kg body weight |
Once daily for 3-5 days |
orally with drinking water or milk replacer |
Swine |
80 ml of product |
orally with drinking water |
|
Poultry (chicks, broilers, replacement chicks, parent flocks) and turkeys |
30 ml of product |
For 3 consecutive days |
CONTRAINDICATIONS
Product is not administered to animals with hypersensitivity to Tilmicosin.
Do not use simultaneously with the ionophores and aminoglycoside group antibiotics, due to the possibility of adverse effects in animals (diarrhea, paresis, nephrotoxic effects). Not to be administered in admixture with a feed containing bentonite.
Not to beadministeredto the layinghensproducingeggs intendedforhuman consumption. Notto beadministeredto ruminants with functionally developed rumen.
WITHDRAWAL PERIOD
For meat: 14 days (swine), 42 (calves) and 12 days (chickens, turkeys), after the last treatment. Meat received before this deadline should be disposedor feed to non-productive animals, depending on the conclusion of the veterinarian.
SHELF LIFE
24 month. After first opening: 14 days when kept in a dark place at +5 to +25° С. After dilution in a drinking water, use within 24 hours.
After dilution in a calf milk replacer, use within 4 hours.
STORAGE CONDITIONS
Store in dark places, out of the reach of children, at +5 to +25°.